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06.03.2024
16 4 minutes read

С того момента, как мир впервые узнал о существовании Covid-19 прошло несколько лет, однако мы по-прежнему многого не знаем об этой болезни и ее последствиях. Так, в первый год пандемии был обнаружен целый букет осложнений после перенесенной инфекции – повышенная утомляемость, одышка, боль в области грудной клетки, потеря обоняния и головные боли. По мере появления новых вариантов SARS-CoV-2 воздействие вируса на организм пришлось пересмотреть – он, как выразился врач-токсиколог Алексей Водовозов, захватывает «тушку» целиком. Это означает, что нет органа или системы, которая не пострадала бы от ковида. Результаты последних исследований также не утешающие – ученые из Великобритании выяснили, что коронавирус оказывает негативное влияние на когнитивные способности и способствует снижению коэффициента IQ на 3-9 баллов.

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Результаты последних исследований показали, что перенесенный COVID-19 приводит к снижению коэффициента IQ

Содержание

  • 1 Пост-ковидный синдром
  • 2 Как COVID-19 влияет на интеллект?
  • 3 Затяжной туман
  • 4 Что дальше?

Пост-ковидный синдром

Мы неоднократно рассказывали о самых разнообразных последствиях перенесенного коронавируса. Известно, что симптомы болезни могут сохраняться долгое время после первоначального выздоровления, а о так называемом пост-ковидном синдроме говорят все чаще. Как правило симптомы длительного COVID-19 проявляются в течение четырех недель после заражения и могут сохраняться месяцами или годами.

Как показали результаты научных исследований, в период от одного до 12 месяцев после заражения ковидом у каждого пятого человека в возрасте от 18 до 64 лет есть по крайней мере одно заболевание вызванное COVID-19. Среди людей в возрасте 65 лет и старше с последствиями перенесенной инфекции сталкивается каждый четвертый.

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Пост-ковидный синдром – крайне распространенное явление

Чаще всего врачи сообщают о таких симптомах пост-ковидного синдрома как
усталость, повышенная температура тела, кашель, одышка и проблемы с пищеварением. Многие пациенты также жалуются на частые головные боли, головокружение, потерю вкуса и обоняния, боль в мышцах и суставах, депрессию и заболевания сердечно-сосудистой системы. И это, разумеется, далеко не все.

Больше по теме: ВОЗ дала определение постковидному синдрому — что это такое?

Как COVID-19 влияет на интеллект?

Ранее мой коллега Андрей Жуков рассказывал о по-настоящему пугающих последствиях перенесенного ковида для мозга. Оказалось, что COVID-19 приводит к нарушениям в мозге, аналогичным тем, которые возникают при черепно-мозговой травме. Более того, выявленные нарушения сохраняются при пост-ковидном синдроме, а снижение активности мозга при этом, эквивалентно его старению на целых 20 лет.

Теперь же ученые сообщают еще более тревожные новости – результаты работы, опубликованной в журнале The New English Journal of Medicine, показали, что
SARS-CoV-2 оказывает влияние на когнитивные способности и память. Исследователи также обнаружили, что после перенесенной инфекции у пациентов, перенесших ковид в легкой форме наблюдались небольшие когнитивные нарушения, эквивалентные снижению IQ на 3 балла в течение 1 года или более после выздоровления. Однако у людей с более тяжелым течением болезни (требующем госпитализации), наблюдалось снижение коэффициента IQ на 9 пунктов.

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Коронавирус приводит к снижению коэффициента IQ на 3-9 баллов

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Авторы научной работы отмечают, что у людей с пост-ковидным синдромом наблюдалось наибольшее снижение коэффициента IQ чем у тех, чьи симптомы исчезли. Наибольший дефицит когнитивных способностей был связан с памятью и мышлением.

Полученные результаты показали, что пациенты, перенесшие COVID-19, выполняли когнитивные тесты медленно и с большим количеством ошибок, чем те, кто не сталкивался с инфекцией. Группой с наибольшим когнитивным дефицитом были пациенты, которые находились в отделении интенсивной терапии во время терапии COVID-19, – говорит Адам Хэмпшир из Имперского колледжа Лондона, один из авторов нового исследования.

Затяжной туман

Несмотря на то, что проблемы с когнитивными способностями после перенесенного коронавируса хорошо известны, существуют ли объективно измеримые когнитивные нарушения и как долго они сохраняются, остается неясным. Чтобы расставить все точки над i авторы исследования пригласили 800 000 взрослых испытуемых перенесших SARS-CoV-2 REACT в Великобритании пройти онлайн-оценку когнитивных способностей в восьми областях. В общей сложности 141 583 участников выполнили хотя бы одно задание, а 112 964 – все восемь.

Ученые оценили когнитивные показатели испытуемых, перенесших SARS-CoV-2 с симптомами, сохраняющимися в течение как минимум 12 недель, независимо от того, исчезли они или нет, а также среди неинфицированных участников исследования. Полученные результаты показали, что по сравнению с теми, кто ни разу не переболел COVID-19, у столкнувшихся с вирусом наблюдалось снижение коэффициента IQ на 3 балла.

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Перенесенный коронавирус негативно сказывается на когнитивных способностях

Это интересно: Длительный COVID разрушает внутренние органы — почему это происходит

В свою очередь столкнувшиеся с пост-ковидным синдромом участники исследования продемонстрировали снижения IQ на 6 баллов, а те, кто был госпитализирован в отделение интенсивной терапии – снижение IQ на 9 баллов.

При этом, как сообщают исследователи, наибольшее снижение коэффициента IQ наблюдалось у людей, инфицированных в начале пандемии исходным вирусом SARS-CoV-2 или вариантом B.1.1.7, в то время у как заболевших в период Омикрона, балл снижение коэффициента был ниже. Авторы работы отмечают, что полученные ими выводы согласуется с другими исследованиями, предполагающими, что связь между когнитивными нарушениями, вызванными с COVID-19, ослабевала по мере прогрессирования пандемии.

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В исследовании приняли участие 800 000 человек, перенесших COVID-19

У переболевших COVID-19 пациентов, прнявших учатие в новом исследовании, наблюдается снижение коэффициента IQ на 3-9 баллов

  • на 3 балла у тех, кто переболел в легкой форме
  • на 6 у столкнувшихся с пост-ковидным синдромом
  • на 9 у госпитализированных в отделение интенсивной терапии

Результаты исследования также показали, что коэффициент IQ среди вакцинированных испытуемых, перенесших COVID-19, был ниже, по сравнению с теми, кто прививку не делал. «Задачи на память, мышление и исполнительные функции были одними из наиболее чувствительных к когнитивным различиям, связанным с COVID-19, и выполнение этих задач различалось в зависимости от продолжительности болезни и госпитализации», – говорится в работе.

Не пропустите: Последняя пандемия: как связаны коронавирус и прионные болезни?

Что дальше?

Полученные результаты вызывают беспокойство, и требуют дальнейших исследований. Так, на момент выхода научной работы, остается несколько нерешенных вопросов, в том числе потенциальные функциональные последствия снижения IQ на 3 балла и предрасполагают ли когнитивные нарушения, связанные с COVID-19, к более высокому риску развития деменции в дальнейшей жизни.

Более глубокое понимание биологии когнитивной дисфункции после заражения SARS-CoV-2 и того, как наилучшим образом ее предотвращать и лечить, имеет решающее значение для удовлетворения потребностей пострадавших лиц и сохранения когнитивного здоровья населения, – сообщают исследователи, которые не принимали участие в работе.

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Последствия коронавируса для мозга оказались намного серьезнее, чем считалось раньше

Комментируя исследование для Medscape Medical News, Жаклин Беккер, клинический нейропсихолог Медицинской школы Икана в Нью-Йорке, отметила, что «одно важное предостережение» заключается в том, что в исследовании использовался онлайн-инструмент оценки когнитивных функций, и поэтому результаты следует учитывать с «долей скептицизма».

Вам будет интересно: Способствует ли коронавирус развитию нейродегенеративных заболеваний?

Тем не менее, в работе действительно большая выборка, а полученные результаты в целом согласуются с тем, что мы наблюдали с точки зрения когнитивного дефицита после COVID-19. Также вполне вероятно, что новое исследование «недооценивает» степень снижения когнитивных способностей, которую можно было бы наблюдать при проведении целого ряда нейропсихологических тестов. К счастью, ранее проведенные исследования в этой области показали, что когнитивные способности как правило улучшаются через 12-18 месяцев после перенесенного COVID-19. Речь идет преимущественно о нарушениях памяти, внимания и скорости обработки информации.

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06.03.2024
16 4 minutes read
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07.11.2023

Как сегодня выглядит озоновая дыра, о которой все говорили в 1990-е годы — Hi-News.ru»>/**/ article{display:block}body{font-size:14px;line-height:1}ol,ul{list-style:none;padding:0;margin:0}html,body{font:400 -apple-system,BlinkMacSystemFont,sans-serif}html,body,div,span,iframe,h1,p,a,img,ins,strong,b,form,article,time{margin:0;padding:0;border:0;font-size:100%;-webkit-text-size-adjust:100%;font-family:-apple-system,BlinkMacSystemFont,sans-serif;vertical-align:baseline;-webkit-font-smoothing:antialiased}body{font-size:14px;line-height:1;min-width:1124px}ol,ul{list-style:none;padding:0;margin:0}b,strong{font-weight:700}img{overflow:hidden;height:auto;max-width:100%;font:400 10px -apple-system,BlinkMacSystemFont,sans-serif}p{color:#000;margin-bottom:15px;font:400 20px/1.5 -apple-system,BlinkMacSystemFont,sans-serif}h1{color:#000;margin:0 0 28px 0;font:700 54px/1 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24.09.2024

Как это работает? | Рамки металлодетектора

28.03.2022

Как живет человек, которого «чипировал» Илон Маск — Hi-News.ru»>/**/ article{display:block}body{font-size:14px;line-height:1}ol,ul{list-style:none;padding:0;margin:0}html,body{font:400 -apple-system,BlinkMacSystemFont,sans-serif}html,body,div,span,iframe,h1,p,a,img,ins,strong,b,form,article,time{margin:0;padding:0;border:0;font-size:100%;-webkit-text-size-adjust:100%;font-family:-apple-system,BlinkMacSystemFont,sans-serif;vertical-align:baseline;-webkit-font-smoothing:antialiased}body{font-size:14px;line-height:1;min-width:1124px}ol,ul{list-style:none;padding:0;margin:0}b,strong{font-weight:700}img{overflow:hidden;height:auto;max-width:100%;font:400 10px -apple-system,BlinkMacSystemFont,sans-serif}p{color:#000;margin-bottom:15px;font:400 20px/1.5 -apple-system,BlinkMacSystemFont,sans-serif}h1{color:#000;margin:0 0 28px 0;font:700 54px/1 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